MISSION
Children are not just small adults. Their bodies and health challenges are unique, including the pathogenesis of autoimmune diseases. Unlike adults, children's immune systems are still developing, which can lead to distinctive patterns in how rheumatic diseases manifest and progress in them. Our mission is not only to unravel the mysteries of pediatric autoimmunity but also to translate our findings into better, child-specific treatments.
RESEARCH PROJECTS
Juvenile idiopathic arthritis (JIA) is the most common form of chronic arthritis in children, yet its underlying mechanisms remain poorly understood. Our lab investigates the molecular and cellular drivers of inflammation in JIA by studying the synovium, the tissue that lines the joints and serves as the primary site of inflammation. By analyzing synovial tissue from JIA patients, we aim to uncover the key pathways and immune responses that contribute to disease development and progression, with the goal of identifying new targets for diagnosis and therapy.
Molecular Mechanisms of Juvenile Idiopathic Arthritis
We have a long-standing interest in how transcription factors regulate lymphocyte development and function. Our research focuses on gene regulation in lymphocytes within the context of autoimmunity and infection, aiming to understand how dysregulated transcriptional programs contribute to immune dysfunction and disease.
Genetic Regulation of Immune Cells
OPEN POSITIONS
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Yomogida lab is seeking graduate students, technicians and post docs who are looking for the opportunity to advance their career. Please contact Kentaro Yomogida (kentaro.yomogida@cuanschutz.edu) for more details.